What drugs do we use?


The most widely used class of antidepressants is selective serotonin reuptake inhibitors (SSRIs), such as fluoxetine, sertraline, paroxetine, and citalopram (see Mood Disorders:Drug therapy). Other classes of antidepressants include serotonin-norepinephrine reuptake inhibitors (SNRIs), such as venlafaxine, duloxetine, or desvenlafaxine, and norepinephrine-dopamine reuptake inhibitors, such as bupropion. Tricyclic antidepressants such as amitriptlyine and nortriptyline are seldom used, unless people also have a disorder causing pain that interferes with activities and work. Monoamine oxidase inhibitors may be effective but are rarely used except when other antidepressants have not worked.

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